The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
Apr. 29, 2011
Jan Roger Karlson, Oslo, NO;
Peer Børretzen, Nærsnes, NO;
Jan Roger Karlson, Oslo, NO;
Peer Børretzen, Nærsnes, NO;
Algeta ASA, Oslo, NO;
Abstract
The present invention relates to a method for the generation ofRa of pharmaceutically tolerable purity comprising: i) preparing a generator mixture comprisingAc,Th andRa in a first aqueous solution comprising a first mineral acid; ii) loading said generator mixture onto a DGA separation medium (e.g. resin); iii) eluting saidRa from said DGA separation medium using a second mineral acid in a second aqueous solution to give an elutedRa solution; and iv) stripping the DGA separation medium of saidAc andTh by flowing a third mineral acid in a third aqueous solution through the DGA separation medium in a reversed direction; The invention further relates to high purity radium-223 formed or formable by such a method as well as pharmaceutical compositions comprising such radium-223 of pharmaceutical purity.