The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
May. 16, 2012
Applicants:
Brian S. J. Blagg, Lawrence, KS (US);
Bhaskar Reddy Kusuma, Lawrence, KS (US);
Inventors:
Brian S. J. Blagg, Lawrence, KS (US);
Bhaskar Reddy Kusuma, Lawrence, KS (US);
Assignee:
THE UNIVERSITY OF KANSAS, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A61K 31/352 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/352 (2013.01); A61K 31/7048 (2013.01);
Abstract
An inhibitor of heat shock protein 90 (HSP90) can include a coumermycin A1 analog having a structure that inhibits HSP90 greater than coumermycin A1. That is, the coumermycin A1 analog is not coumermycin A1. The coumermycin A1 analog can have an antiproliferative biological activity, which can be superior to coumermycin A1. The activity can include the coumermycin A1 analog inhibiting a C-terminus of HSP90.