IDiyas

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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9056096 B1

PDFFull Text
Date of Patent:
Jun. 16, 2015

Filed:

Jun. 03, 2011

Hyaluronic acid decomposition-promoting factor and inhibitor thereof

Applicants:

Hiroyuki Yoshida, Odawara, JP;

Shintaro Inoue, Odawara, JP;

Shingo Sakai, Odawara, JP;

Aya Nagaoka, Odawara, JP;

Inventors:

Hiroyuki Yoshida, Odawara, JP;

Shintaro Inoue, Odawara, JP;

Shingo Sakai, Odawara, JP;

Aya Nagaoka, Odawara, JP;

Assignee:

Kao Corporation, Tokyo, JP;

Attorney:

Sterne, Kessler, Goldstein & Fox P.L.L.C.

Primary Examiner:

Maher Haddad

Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 39/395 (2006.01); A61K 8/42 (2006.01); A61K 8/44 (2006.01); A61K 8/49 (2006.01); A61K 31/365 (2006.01); A61K 31/4015 (2006.01); A61K 31/5415 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 48/00 (2006.01); A61Q 19/08 (2006.01); C07K 14/47 (2006.01); C07K 16/40 (2006.01); C12N 15/113 (2010.01); G01N 33/50 (2006.01); A61K 31/16 (2006.01); A61K 31/198 (2006.01); A61K 31/7048 (2006.01); C07K 7/08 (2006.01); C07K 16/18 (2006.01); C12Q 1/02 (2006.01); A61K 8/64 (2006.01); A61K 8/73 (2006.01); A61K 31/728 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 8/42 (2013.01); A61K 8/44 (2013.01); A61K 8/49 (2013.01); A61K 8/4913 (2013.01); A61K 8/498 (2013.01); A61K 31/365 (2013.01); A61K 31/4015 (2013.01); A61K 31/5415 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/00 (2013.01); A61K 48/005 (2013.01); A61K 2800/782 (2013.01); A61Q 19/08 (2013.01); C07K 14/47 (2013.01); C07K 16/40 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); G01N 33/5023 (2013.01); A61K 31/16 (2013.01); A61K 31/198 (2013.01); A61K 31/7048 (2013.01); C07K 7/08 (2013.01); C07K 16/18 (2013.01); C12Q 1/025 (2013.01); C07K 2317/34 (2013.01); A61K 8/64 (2013.01); A61K 8/735 (2013.01); C12N 2310/11 (2013.01); G01N 2500/10 (2013.01); A61K 31/728 (2013.01); G01N 2400/40 (2013.01);
Abstract

The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.

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