The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
Jun. 13, 2006
Applicants:
Stefano Colloca, Rome, IT;
Antonella Folgori, Rome, IT;
Armin Lahm, Rome, IT;
Alfredo Nicosia, Rome, IT;
Inventors:
Stefano Colloca, Rome, IT;
Antonella Folgori, Rome, IT;
Armin Lahm, Rome, IT;
Alfredo Nicosia, Rome, IT;
Assignee:
MSD Italia SRL, Rome, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); A61K 39/29 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); C07K 14/005 (2013.01); C07K 2319/00 (2013.01); C12N 2710/10343 (2013.01); C12N 2770/24222 (2013.01); C12N 2770/24234 (2013.01);
Abstract
The present invention features nucleic acid constructs that can be used as a HCV nucleic acid vaccine, vaccine component, or in the production of a HCV vaccine. Described constructs include those: (1) encoding for a chimeric HCV polypeptide containing a NS3-4A region based on a first HCV strain and an NS3-NS4A-NS4B-NS5A or an NS3-NS4A-NS4B-NS5A-NS5B region based on a second strain; and (2) a chimpanzee based adenovector encoding an HCV polypeptide.