The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

May. 22, 2009
Applicants:

Dakai Liu, South Setauket, NY (US);

Xiaofeng LI, Farmington, CT (US);

Richard Jin, Pennington, NJ (US);

Yuaxin Liang, South Setauket, NY (US);

Wei Cheng, Seaford, NY (US);

Riddhi Bhattacharyya, West Babylon, NY (US);

Guangrong Zhang, Shrewsbury, MA (US);

Inventors:

Dakai Liu, South Setauket, NY (US);

Xiaofeng Li, Farmington, CT (US);

Richard Jin, Pennington, NJ (US);

Yuaxin Liang, South Setauket, NY (US);

Wei Cheng, Seaford, NY (US);

Riddhi Bhattacharyya, West Babylon, NY (US);

Guangrong Zhang, Shrewsbury, MA (US);

Assignee:

Enzo Biochem, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/538 (2006.01); G01N 33/68 (2006.01); C40B 30/02 (2006.01); C07D 265/28 (2006.01); C07D 265/38 (2006.01); C07D 265/34 (2006.01); A61K 31/536 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6845 (2013.01); A61K 31/538 (2013.01); C07D 265/38 (2013.01); C07D 265/28 (2013.01); C07D 265/34 (2013.01); A61K 31/536 (2013.01); C40B 30/02 (2013.01); G01N 2800/36 (2013.01);
Abstract

The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.


Find Patent Forward Citations

Loading…