The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
May. 30, 2008
Applicants:
Margot Thome, Mezieres, CH;
Fabien Rebeaud, Epalinges, CH;
Stephan Hailfinger, Lausanne, CH;
Inventors:
Assignee:
University of Lausanne, Lausanne, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); G01N 31/22 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); C12Q 2521/537 (2013.01); G01N 2500/02 (2013.01);
Abstract
The present invention is based on the surprising finding of a proteolytic cleavage function of human Malt1. More particularly, the present invention relates to enzyme and screening assays, methods for assessing cleaving activity, methods for screening, isolated polypeptides, antibodies and inhibitors of Malt1. The present invention also relates to the use of Malt1 as a proteolytic enzyme and the use of compounds comprising a peptide comprising an amino acid sequence according to any one of SEQ ID NO: 1-47 as substrates susceptible for specific proteolytic cleavage.