The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Aug. 14, 2013
Applicant:
The Cleveland Clinic Foundation, Clevland, OH (US);
Inventors:
Jonathan D. Smith, Shaker Heights, OH (US);
Stanley L. Hazen, Pepper Pike, OH (US);
Assignee:
The Cleveland Clinic Foundation, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/775 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/40 (2006.01); A61K 38/17 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/775 (2013.01); A61K 38/00 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 38/1709 (2013.01);
Abstract
A method of ameliorating one or more symptoms of an inflammatory condition in a subject comprises the step of administering to the subject a therapeutically effective amount of a polypeptide that is capable promoting cholesterol efflux from lipid loaded cells, the polypeptide consisting of the amino acid sequence of SEQ ID NO:1, in which each X in SEQ ID NO:1 is a phenylalanine amino acid.