The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Oct. 17, 2014
Applicant:

Astellas Pharma Inc., Chuo-ku, JP;

Inventors:

Nobuyuki Shiraishi, Tokyo, JP;

Hiroaki Hoshii, Tokyo, JP;

Wataru Hamaguchi, Tokyo, JP;

Eriko Honjo, Tokyo, JP;

Tomofumi Takuwa, Tokyo, JP;

Yuji Kondo, Tokyo, JP;

Takayuki Goto, Tokyo, JP;

Assignee:

Astellas Pharma Inc., Chuo-ku, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); C07D 495/10 (2006.01); C07D 495/08 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07D 495/04 (2013.01); C07D 495/10 (2013.01); C07D 495/08 (2013.01);
Abstract

A sulfur-containing bicyclic compound having a PAM action of GABA, and it use for preventing and/or treating schizophrenia, CIAS, cognitive impairment, fragile X syndrome, autism spectrum disorder, spasticity, anxiety disorder, substance addiction, pain, fibromyalgia, or Charcot-Marie-Tooth disease. A pharmaceutical composition for preventing and/or treating schizophrenia, cognitive impairment associated with schizophrenia (CIAS), cognitive impairment, fragile X syndrome, autism spectrum disorder, spasticity, anxiety disorder, substance addiction, pain, fibromyalgia, Charcot-Marie-Tooth disease, or the like, which has a positive allosteric modulator (PAM action) of GABA.


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