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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9051337 B1

PDFFull Text
Date of Patent:
Jun. 09, 2015

Filed:

Mar. 14, 2014

Substituted 10-hydroxy-9,11-dioxo-2,3,4a,5,9,11,13,13a-octahydro-1h-pyrido[1,2-a]pyrrolo[1',2′:3,4]imidazo[1,2-d]pyrazine-8-carboxamides

Applicants:

Shionogi & Co., Ltd., Osaka, JP;

Viiv Healthcare Company;

Inventors:

Brian A. Johns, Research Triangle Park, NC (US);

Takashi Kawasuji, Osaka, JP;

Teruhiko Taishi, Osaka, JP;

Yoshiyuki Taoda, Osaka, JP;

Assignees:

Shionogi & Co., Ltd., Osaka, JP;

ViiV Healthcare Company, Research Triangle Park, NC (US);

Attorney:

Wenderoth, Lind & Ponack, L.L.P.

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 241/38 (2006.01); C07D 498/22 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 498/04 (2006.01); C07D 471/22 (2006.01); C07D 498/14 (2006.01); C07D 498/20 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); C07D 471/04 (2013.01); C07D 471/14 (2013.01); C07D 498/04 (2013.01); C07D 471/22 (2013.01); C07D 498/14 (2013.01); C07D 498/20 (2013.01);
Abstract

The present invention is to provide a novel compound (I) shown below, having the anti-virus activity; particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. (wherein

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