The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Sep. 05, 2013
Applicant:
Vertex Pharmaceuticals Incorporated, Cambdridge, MA (US);
Inventors:
Hayley Binch, Encinitas, CA (US);
Peter D. J. Grootenhuis, San Diego, CA (US);
Albert Pierce, Cambridge, MA (US);
Lev T. D. Fanning, San Marcos, CA (US);
Assignee:
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to compounds of formula IVA, formula IVB, or formula IVC, useful as modulators of ATP-Binding Cassette ('ABC') transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators.