The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Feb. 13, 2012
Applicants:

Dieter Dorsch, Ober-Ramstadt, DE;

Alfred Jonczyk, Darmstadt, DE;

Guenter Hoelzemann, Seeheim-Jugenheim, DE;

Christiane Amendt, Muehltal/Trautheim, DE;

Frank Zenke, Darmstadt, DE;

Inventors:

Dieter Dorsch, Ober-Ramstadt, DE;

Alfred Jonczyk, Darmstadt, DE;

Guenter Hoelzemann, Seeheim-Jugenheim, DE;

Christiane Amendt, Muehltal/Trautheim, DE;

Frank Zenke, Darmstadt, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 471/04 (2006.01); A61K 45/06 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4985 (2013.01); A61K 45/06 (2013.01); C07D 491/048 (2013.01);
Abstract

The present invention relates to novel pyrido[2,3-b]pyrazine compounds of formula (I): and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.


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