The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Dec. 20, 2013
Applicant:
Gilead Sciences, Inc., Foster City, CA (US);
Inventor:
Gregory Notte, San Mateo, CA (US);
Assignee:
Gildead Sciences, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01);
Abstract
The present invention relates to compounds of Formula (I): Wherein variables are as defined above. The compounds have apoptosis signal-regulating kinase ('ASK1') inhibitory activity, and are thus useful in the treatment of ASK1-mediated conditions, including autoimmune disorders, inflammatory diseases, cardiovascular diseases, diabetes, diabetic nephropathy, cardio-renal diseases, including kidney disease, fibrotic diseases, respiratory diseases, COPD, idiopathic pulmonary fibrosis, acute lung injury, acute and chronic liver diseases, and neurodegenerative diseases.