The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Jul. 29, 2014
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Guenter Hoelzemann, Seeheim-Jugenheim, DE;
Dieter Dorsch, Ober-Ramstadt, DE;
Alfred Jonczyk, Darmstadt, DE;
Christiane Amendt, Muehltal/Trautheim, DE;
Frank Zenke, Darmstadt, DE;
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 213/74 (2006.01); C07D 471/04 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61K 31/4375 (2006.01); A61K 31/497 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/4439 (2013.01); C07D 213/74 (2013.01); C07D 471/04 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61K 31/4375 (2013.01); A61K 31/497 (2013.01);
Abstract
The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.