The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Jan. 15, 2009
Applicants:
Nicolas Winssinger, Strasbourg, FR;
Sofia Barluenga, Strasbourg, FR;
Martin Karplus, Cambridge, MA (US);
Inventors:
Nicolas Winssinger, Strasbourg, FR;
Sofia Barluenga, Strasbourg, FR;
Martin Karplus, Cambridge, MA (US);
Assignee:
UNIVERSITE DE STRASBOURG, Strasbourg, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/14 (2006.01); C07D 225/06 (2006.01); C07D 313/00 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); A61K 31/435 (2006.01); A61K 31/4453 (2006.01); A61K 31/335 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/435 (2013.01); C07D 211/14 (2013.01); C07D 225/06 (2013.01); A61K 31/4453 (2013.01); A61K 31/335 (2013.01); C07D 313/00 (2013.01); C07D 405/14 (2013.01);
Abstract
Disclosed are macrocyclic compounds of formulae I, I', II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.