The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Aug. 10, 2010
Applicant:

Cedric Bouteiller, Vulbens, FR;

Inventor:

Cedric Bouteiller, Vulbens, FR;

Assignee:

ADVANCED ACCELERATOR APPLICATIONS, Saint-Genis-Pouilly, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 327/04 (2006.01); A61K 51/04 (2006.01); A61K 51/08 (2006.01); C07K 1/13 (2006.01);
U.S. Cl.
CPC ...
C07D 327/04 (2013.01); A61K 51/04 (2013.01); A61K 51/08 (2013.01); C07K 1/13 (2013.01); A61K 51/082 (2013.01);
Abstract

The invention relates to polysultone derivatives used as precursors to radiolabelled macromolecules usable for medicine and in nuclear imaging. The aim of the invention is to provide novel prosthetic compounds or groupings, the synthesis of which is straightforward, easy and automatable, enabling access to economical and effective radiolabelled macromolecules. The aim is achieved by the invention, which involves compounds of formula 10 or 11. Said double-sultone derivatives are produced by opening the sultone rings using a nucleophile radical Rwhich may be a radionucleide R* for one of the sultone rings and an active radical peptide Rfor the other sultone ring. The invention also relates to the method for producing the abovementioned compounds, as well as to the drugs or diagnosis products that the latter are capable of forming.


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