The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Apr. 28, 2011
Applicants:
Simon Feldbæk Nielsen, Ballerup, DK;
Anne Marie Horneman, Ballerup, DK;
Jesper Lau, Farum, DK;
Jens Christian Højland Larsen, Ballerup, DK;
Inventors:
Simon Feldbæk Nielsen, Ballerup, DK;
Anne Marie Horneman, Ballerup, DK;
Jesper Lau, Farum, DK;
Jens Christian Højland Larsen, Ballerup, DK;
Assignee:
LEO PHARMA A/S, Ballerup, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5375 (2006.01); C07C 49/755 (2006.01); A61K 31/122 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 35/00 (2006.01); A61P 17/14 (2006.01); C07C 317/22 (2006.01); C07D 305/06 (2006.01); A61K 31/337 (2006.01); C07C 235/42 (2006.01); A61K 31/166 (2006.01); C07C 311/29 (2006.01); A61K 31/18 (2006.01); C07D 307/88 (2006.01); A61K 31/365 (2006.01); C07D 407/12 (2006.01); C07D 209/46 (2006.01); A61K 31/4035 (2006.01); C07D 405/12 (2006.01); C07D 265/30 (2006.01); C07D 307/83 (2006.01); C07D 233/34 (2006.01); C07D 233/36 (2006.01); C07C 235/48 (2006.01);
U.S. Cl.
CPC ...
C07D 307/83 (2013.01); C07D 233/34 (2013.01); C07D 233/36 (2013.01); C07D 305/06 (2013.01); C07D 209/46 (2013.01); C07C 49/755 (2013.01); C07C 235/48 (2013.01); C07C 311/29 (2013.01); C07D 307/88 (2013.01);
Abstract
Novel biaryl compounds with phosphodiesterase inhibitory activity of general formula (I) below, wherein R1, R2, R3, X, Y, Z, Z, Z, and Zhave the meanings defined herein, as well as their use as therapeutic agents in the treatment of inflammatory diseases and conditions are described herein.