The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Sep. 24, 2014
Georg Dahmann, Warthausen-Birkenhard, DE;
Holger Wagner, Mettenberg, DE;
Matthias Eckhardt, Biberach an der Riss, DE;
Markus Frank, Ulm, DE;
Marco Santagostino, Mittelbiberach, DE;
Juergen Schnaubelt, Oberhoefen/Warthausen, DE;
Uwe Stertz, Biberach an der Riss, DE;
Thorsten Pachur, Biberach an der Riss, DE;
Georg Dahmann, Warthausen-Birkenhard, DE;
Holger Wagner, Mettenberg, DE;
Matthias Eckhardt, Biberach an der Riss, DE;
Markus Frank, Ulm, DE;
Marco Santagostino, Mittelbiberach, DE;
Juergen Schnaubelt, Oberhoefen/Warthausen, DE;
Uwe Stertz, Biberach an der Riss, DE;
Thorsten Pachur, Biberach an der Riss, DE;
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
The present invention relates to compounds of formula I wherein Rdenotes F or CF, Rdenotes H or C-alkyl and Z denotes a leaving group or an optionally substituted or protected hydroxyl group, suitable as intermediates in the synthesis of indanyloxydihydrobenzofuranylacetic acids, which are GPR40 agonists, to a process for preparing these intermediates and to the process for preparing the GPR40 agonists making use of an asymmetric catalytic hydrogenation reaction in the presence of a transition metal catalyst and a chiral auxiliary.