The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
May. 19, 2014
Applicant:
Astex Therapeutics, Ltd., Cambridge, GB;
Inventors:
Valerio Berdini, Cambridge, GB;
Michael Alistair O'Brien, Cambridge, GB;
Maria Grazia Carr, Cambridge, GB;
Theresa Rachel Early, Cambridge, GB;
Adrian Liam Gill, Cheshire, GB;
Gary Trewartha, Cambridge, GB;
Alison Jo-Anne Woolford, Cambridge, GB;
Andrew James Woodhead, Cambridge, GB;
Paul Graham Wyatt, Perth, GB;
Assignee:
ASTEX THERAPEUTICS, LTD., Cambridge, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 401/12 (2006.01); C07D 231/38 (2006.01); A61K 31/4152 (2006.01); A61K 31/416 (2006.01); A61K 31/454 (2006.01); C04B 35/632 (2006.01); C07D 231/14 (2006.01); C07D 231/40 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 453/02 (2006.01); C07D 471/04 (2006.01); A61K 31/415 (2006.01); A61K 31/4155 (2006.01); A61K 31/4178 (2006.01); A61K 31/4196 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 231/38 (2013.01); A61K 31/4152 (2013.01); A61K 31/416 (2013.01); A61K 31/454 (2013.01); C04B 35/632 (2013.01); C07D 231/14 (2013.01); C07D 231/40 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 453/02 (2013.01); C07D 471/04 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/4178 (2013.01); A61K 31/4196 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention provides compounds of the formula (0) or salts or tautomers or N-oxides or solvates thereof for use in the prophylaxis or treatment of disease states and conditions such as cancers mediated by cyclin-dependent kinase and glycogen synthase kinase-3. In formula (0):