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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9051248 B1

PDFFull Text
Expired
Date of Patent:
Jun. 09, 2015

Filed:

Aug. 06, 2010

Methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid

Applicants:

Xianqi Kong, Dollard-des-Ormeaux, CA;

Nigel Levens, Beaconsfield, CA;

Abderrahim Bouzide, Mississauga, CA;

Stephane Ciblat, Montreal, FR;

Richard Frenette, Laval, CA;

Johanne Renaud, Laval, CA;

Inventors:

Xianqi Kong, Dollard-des-Ormeaux, CA;

Nigel Levens, Beaconsfield, CA;

Abderrahim Bouzide, Mississauga, CA;

Stephane Ciblat, Montreal, FR;

Richard Frenette, Laval, CA;

Johanne Renaud, Laval, CA;

Assignee:

BHI Limited Partnership, Laval, CA;

Attorneys:

McCarter & English, LLP

Danielle L. Herritt

Emily Dertz

Primary Examiner:

Joseph Kosack

Assistant Examiner:

Matthew Coughlin

Int. Cl.
CPC ...
C07C 309/65 (2006.01); C07D 319/06 (2006.01); A61K 31/366 (2006.01); A61K 31/365 (2006.01); A61K 31/255 (2006.01); C07D 309/22 (2006.01); A61K 31/351 (2006.01); C07C 309/05 (2006.01); C07C 311/06 (2006.01); C07C 311/51 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07D 231/12 (2006.01); C07D 307/33 (2006.01); C07D 307/58 (2006.01); C07D 307/77 (2006.01); C07D 327/10 (2006.01); C07F 9/09 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07C 309/65 (2013.01); C07D 319/06 (2013.01); A61K 31/366 (2013.01); A61K 31/365 (2013.01); A61K 31/255 (2013.01); C07D 309/22 (2013.01); A61K 31/351 (2013.01); C07C 309/05 (2013.01); C07C 311/06 (2013.01); C07C 311/51 (2013.01); C07C 2101/04 (2013.01); C07C 2101/14 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 231/12 (2013.01); C07D 307/33 (2013.01); C07D 307/58 (2013.01); C07D 307/77 (2013.01); C07D 327/10 (2013.01); C07F 9/091 (2013.01); C07F 9/4006 (2013.01);
Abstract

The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in vitro or in vivo. The invention also relates to sulfonate ester prodrugs of 1,3PDS as well as Gemini dimmers and oligomers of 1,3PDS for the prevention or treatment of associated diseases and conditions.

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