The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Mar. 13, 2013
Applicants:

Stephen J. Connon, Dublin, IE;

Sean Tallon, Dublin, IE;

Claudio Cornaggia, Dublin, IE;

Francesco Manoni, Dublin, IE;

Esther Torrente, Dublin, IE;

Inventors:

Stephen J. Connon, Dublin, IE;

Sean Tallon, Dublin, IE;

Claudio Cornaggia, Dublin, IE;

Francesco Manoni, Dublin, IE;

Esther Torrente, Dublin, IE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 409/04 (2006.01); C07D 311/20 (2006.01); C07D 307/33 (2006.01); C07D 311/76 (2006.01); C07D 453/04 (2006.01); C07B 53/00 (2006.01); B01J 31/02 (2006.01);
U.S. Cl.
CPC ...
B01J 31/0271 (2013.01); C07D 311/76 (2013.01); C07B 53/00 (2013.01); C07D 453/04 (2013.01); C07D 307/33 (2013.01); C07D 311/20 (2013.01); C07D 409/04 (2013.01);
Abstract

Disclosed herein is enantioselective synthetic method comprising reacting an enolisable C-Corganic anhydride with a second compound selected from the group consisting of an aldehyde, a ketone, an aldimine, a ketimine or a Michael Acceptor in the presence of a bifunctional organocatalyst. The reaction may find particular utility in the enantioselective synthesis of medicinally relevant heterocycles, such as dihydroisocoumarins and dihydroisoquinolinones.


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