The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Oct. 22, 2012
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Gurdip Bhalay, Horsham, GB;

Lee Edwards, Patridge Green, GB;

Catherine Howsham, Horsham, GB;

Peter Hunt, Storrington, GB;

Nichola Smith, Horsham, GB;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 241/10 (2006.01); C07D 471/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); C07D 471/10 (2013.01);
Abstract

Compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, R, R, R, R, R, and Rhave the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.


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