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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9050321 B1

PDFFull Text
Date of Patent:
Jun. 09, 2015

Filed:

Sep. 26, 2008

Rationally-designed anti-αβν6 integrin antibody mfevp1 and variants thereof, method of making such antibody and the use thereof in treating and diagnosis of disease

Applicants:

Kerry Chester, London, GB;

Heide Kogelberg, London, GB;

John F. Marshall, London, GB;

Inventors:

Kerry Chester, London, GB;

Heide Kogelberg, London, GB;

John F. Marshall, London, GB;

Assignee:

Cancer Research Technology Limited, London, GB;

Attorneys:

Patrick J. Hagan

Dann, Dorfman, Herrell and Skillman

Primary Examiner:

Hong Sang

Assistant Examiner:

Michael D Allen

Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); C12N 15/63 (2006.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 39/39541 (2013.01); C07K 16/2839 (2013.01); C07K 16/3007 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/77 (2013.01); C07K 2318/10 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to antibodies that are obtained by inserting an amino acid sequence capable of binding to a target into the complementarity determining region (CDR) of a parent antibody. The antibody thus obtained has a new binding specificity. For example, the antibodies of the present invention are able to bind to the target, such as αvβ6 integrin, while retaining one or more of the useful properties of the parent antibody.

Find Patent Forward Citations

Chester, Kerry. (2015). Rationally-designed anti-αβν6 integrin antibody mfevp1 and variants thereof, method of making such antibody and the use thereof in treating and diagnosis of disease (U.S. Patent No. 9050321). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9050321

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