The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2015
Filed:
Sep. 23, 2014
Chung-ang University Industry-academy Cooperation Foundation, Seoul, KR;
Chungbuk National University Industry-academic Cooperation Foundation, Cheongju-si, Chungcheongbuk-do, KR;
Industry Academic Cooperation Foundation, Hallym University, Chuncheon-si, Gangwon-do, KR;
Jae Chan Kim, Seoul, KR;
Kyoung Woo Kim, Seoul, KR;
Yeoun Sook Chun, Seoul, KR;
Soo Hyun Park, Seoul, KR;
Sung Wook Wee, Seoul, KR;
Soo Ik Chang, Daejeon, KR;
Kyong Mi Min, Cheongju-si, KR;
Kyu Wan Kim, Cheongju-si, KR;
Young Joo Shin, Seoul, KR;
CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION, Seoul, KR;
CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Chungcheongbuk-Do, KR;
INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY, Gangwon-Do, KR;
Abstract
Provided is a pharmaceutical composition for treating corneal endothelium wounds, the composition including angiogenin as an effective ingredient. The present invention relates to a new topical therapeutic use of angiogenin for treatment of corneal endothelium wounds, wherein the angiogenin that is generally known to be involved in angiogenesis activates a PI3K/Akt/eNOS pathway thereof in ocular corneal endothelium to increase migration and proliferation of corneal endothelial cells that are not capable of self-proliferation and to promote prevention and treatment of corneal endothelial cell wounds.