The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 2015

Filed:

Mar. 10, 2010
Applicants:

Dennis E. Discher, Philadelphia, PA (US);

Richard Kuo-an Tsai, Boston, MA (US);

Inventors:

Dennis E. Discher, Philadelphia, PA (US);

Richard Kuo-An Tsai, Boston, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); C07K 14/705 (2006.01); A61K 39/12 (2006.01); A61K 47/48 (2006.01); C12N 7/00 (2006.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5184 (2013.01); C07K 14/705 (2013.01); A61K 35/13 (2013.01); A61K 39/12 (2013.01); A61K 47/48776 (2013.01); A61K 48/00 (2013.01); A61K 2039/5256 (2013.01); C12N 7/00 (2013.01); C12N 2740/15051 (2013.01);
Abstract

The present invention relates to a viral particle. The viral particle has a radius of less than about 1 μm, and at least one peptide comprising at least a biologically active portion of CD47. The present invention also includes a method of increasing the life of a particle in vivo in a mammal. The method includes the steps of expressing at least one peptide comprising at least a biologically active portion of CD47 in a viral particle, and administering the viral particle having CD47 expressed to a mammal, wherein the administered viral particle has a longer half life in the mammal than an otherwise identical viral particle that does not have CD47 expressed thereon.


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