The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Mar. 26, 2014
Applicant:

Quest Diagnostics Investments Incorporated, Wilmington, DE;

Inventors:

Michael P. Caulfield, San Clemente, CA (US);

Richard E Reitz, San Clemente, CA (US);

Shuguang Li, Abington, PA (US);

Gloria Kwangja Lee, Ladera Ranch, CA (US);

Ronald Krauss, Berkeley, CA (US);

Patricia J. Blanche, Berkeley, CA (US);

W. Henry Benner, Danville, CA (US);

Earl Cornell, Antioch, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/02 (2006.01); G01N 33/92 (2006.01); C07K 1/14 (2006.01); G06F 19/10 (2011.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); C07K 1/14 (2013.01); G01N 15/0266 (2013.01); G06F 19/10 (2013.01);
Abstract

The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention.


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