The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

May. 27, 2010
Applicants:

Yen Nee Tan, Singapore, SG;

Xiaodi Su, Singapore, SG;

Inventors:

Yen Nee Tan, Singapore, SG;

Xiaodi Su, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/553 (2006.01); G01N 33/68 (2006.01); G01N 33/543 (2006.01); G01N 33/539 (2006.01); G01N 33/74 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6803 (2013.01); G01N 33/74 (2013.01); G01N 33/54346 (2013.01); G01N 33/539 (2013.01); G01N 33/587 (2013.01); C12Q 2565/113 (2013.01);
Abstract

The present invention refers to a method of determining protein-nucleic acid interaction. The method comprises mixing a protein with a sample comprising a nucleic acid which is suspected to interact with the protein to form a first mixture. The first mixture can be incubated to allow interaction between the protein and nucleic acid. Metallic nanoparticles are added to the first mixture to obtain a second mixture. An electrolyte is added to the first or second mixture to determine the protein-nucleic acid interaction. The present invention also refers to a kit for determining protein-nucleic acid interaction. The kit comprises a protein capable of interacting with a nucleic acid or a nucleic acid capable of interacting with a protein, and at least one type of metallic nanoparticle.


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