The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Feb. 11, 2008
Ramakrishna Sista, Morrisville, NC (US);
Vamsee K. Pamula, Durham, NC (US);
Michael G. Pollack, Durham, NC (US);
Vijay Srinivasan, Durham, NC (US);
Allen E. Eckhardt, Durham, NC (US);
Richard B. Fair, Durham, NC (US);
Ramakrishna Sista, Morrisville, NC (US);
Vamsee K. Pamula, Durham, NC (US);
Michael G. Pollack, Durham, NC (US);
Vijay Srinivasan, Durham, NC (US);
Allen E. Eckhardt, Durham, NC (US);
Richard B. Fair, Durham, NC (US);
ADVANCED LIQUID LOGIC, INC., San Diego, CA (US);
DUKE UNIVERSITY, Durham, NC (US);
Abstract
A method of providing a droplet in contact with a magnetically responsive bead and having a reduced quantity of a substance. The method generally includes the steps of (a) providing a droplet actuator () comprising: (i) a substrate () comprising electrodes () arranged for conducting droplet operations on a surface; (ii) a starting droplet () comprising: (1) one or more magnetically responsive beads (); (2) a starting quantity of the substance; and (3) a starting volume; (b) magnetically immobilizing the one or more magnetically responsive beads at a location which is at a distance from a target droplet splitting zone, (); (c) conducting one or more droplet operations comprising droplet dividing operations selected to divide the combined droplet to yield a set of droplets comprising: (i) a droplet () comprising substantially all of the one or more magnetically responsive beads and having a decreased quantity of the substance relative to the starting concentration; and (ii) a droplet () substantially lacking the magnetically responsive beads.