The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Mar. 03, 2010
Applicants:
Antje Gupta, Wiesbaden, DE;
Maria Bobkova, Wiesbaden, DE;
Anke Tschentscher, Eltville-Hattenheim, DE;
Inventors:
Antje Gupta, Wiesbaden, DE;
Maria Bobkova, Wiesbaden, DE;
Anke Tschentscher, Eltville-Hattenheim, DE;
Assignee:
IEP GMBH, Wiesbaden, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/22 (2006.01); C12N 9/02 (2006.01); C12P 7/42 (2006.01); C12P 7/02 (2006.01); C12P 7/06 (2006.01); C12P 7/16 (2006.01); C12P 7/18 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C12N 9/0004 (2013.01); C12P 7/02 (2013.01); C12P 7/06 (2013.01); C12P 7/16 (2013.01); C12P 7/18 (2013.01); C12P 7/22 (2013.01); Y02E 50/17 (2013.01); Y02E 50/10 (2013.01);
Abstract
In a process for the stereoselective, in particular enantioselective enzymatic reduction of keto compounds to the corresponding chiral hydroxy compounds, wherein the keto compounds are reduced with an enantioselective, NADH-specific oxidoreductase, a polypeptide is used for reducing the keto compounds, which polypeptide exhibits an R-ADH-signature H-[P; A]-[I; A; Q; V; L]-[G; K]-R at positions 204-208 and the following further structural features in their entirety: