The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Oct. 09, 2012
Applicant:
Jiangsu Genecon Biotechnologies Co., Ltd., Nantong, CN;
Inventors:
Yuanyuan Zhu, Jiangsu, CN;
Tiejun Li, Jiangsu, CN;
Assignee:
Jiangsu Genecon Biotechnologies Co., Ltd., Nantong, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 8/60 (2006.01); A61Q 19/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/14 (2013.01); A61K 8/606 (2013.01); A61Q 19/02 (2013.01); A61K 2800/42 (2013.01);
Abstract
Provided is a double-chain siRNA molecule targeting a microphthalmia-associated transcription factor MITF coding gene. A sense strand of the siRNA molecule has a sequence of SEQ ID NO: 3 and an anti-sense strand has a sequence of SEQ ID NO: 4, and the anti-sense strand specifically binds to mRNA of the MITF coding gene, to degrade the mRNA, thereby reducing the synthesis of melanin. Further provided is an application of the siRNA molecule in freckle whitening cosmetics or the preparation of medicines for treatment of diseases related to melanin gene.