The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Jan. 13, 2005
Applicants:

Stefan Barth, Roetgen, DE;

Mehmet Kemal Tur, Koln, DE;

Michael Stöcker, Aachen, DE;

Rainer Fischer, Monschau, DE;

Inventors:

Stefan Barth, Roetgen, DE;

Mehmet Kemal Tur, Koln, DE;

Michael Stöcker, Aachen, DE;

Rainer Fischer, Monschau, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 9/12 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
C12N 9/12 (2013.01); C07K 2319/01 (2013.01); C12N 15/62 (2013.01);
Abstract

A synthetic, soluble, endogenous complex formed from at least one component A and at least one component B, whereby component A comprises a binding domain for extra-cellular surface structures that internalize upon binding of component A of said complex, and component B has a constitutive catalytic kinase activity and effects cell biosynthesis/signalling including cell death after internalization. The complex allows to influence the growth and the physiology of cells. In particular said complex, nucleic acid molecules encoding it, cells transfected or transformed with these nucleic acid molecules are usable for the preparation of medicaments for the treatment of proliferative diseases, inflammatory diseases, allergies and autoimmune diseases.


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