The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Aug. 28, 2012
Sangkon OH, Baltimore, MD (US);
Jacques F. Banchereau, Montclair, NJ (US);
Gerard Zurawski, Midlothian, TX (US);
Hideki Ueno, Plano, TX (US);
Ling NI, Dallas, TX (US);
SangKon Oh, Baltimore, MD (US);
Jacques F. Banchereau, Montclair, NJ (US);
Gerard Zurawski, Midlothian, TX (US);
Hideki Ueno, Plano, TX (US);
Ling Ni, Dallas, TX (US);
Baylor Research Institute, Dallas, TX (US);
Abstract
The present invention includes compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of allergy, and asthma.