The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Jan. 16, 2013
Applicant:
The Doshisha, Kyoto-shi, Kyoto, JP;
Inventors:
Assignee:
THE DOSHISHA, Kyoto, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 4/00 (2006.01); C07K 14/00 (2006.01); A61P 25/28 (2006.01); C07K 7/06 (2006.01); C07K 14/81 (2006.01); C07K 14/47 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); C07K 14/81 (2013.01); C07K 14/8142 (2013.01); C07K 14/4711 (2013.01); A61K 38/00 (2013.01); C07K 14/00 (2013.01);
Abstract
A primary object of the present invention is to develop a compound that specifically inhibits the production of Aβ protein and serves as an active ingredient of a drug to treat and/or prevent Alzheimer's disease. This object can be achieved by a polypeptide having the amino acid sequence represented by any one of SEQ ID NOs: 1, 13, 14, and 22, that binds to the N-terminal region of βCTF; a γ-secretase activity inhibitor containing the polypeptide; β-secretase activity inhibitor; Aβ protein production inhibitor; and an agent for treating and/or preventing Alzheimer's disease.