The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Aug. 24, 2011
Applicants:

Mingqi LI, Chengdu, CN;

Han Wang, Chengdu, CN;

Qimin Deng, Chengdu, CN;

Zuoyong Cheng, Chengdu, CN;

Maoliang LI, Chengdu, CN;

Yonglong Zeng, Chengdu, CN;

Xue Jiang, Chengdu, CN;

Yuchun Duan, Chengdu, CN;

Sanping Zhu, Chengdu, CN;

Dezhong Wen, Chengdu, CN;

Inventors:

Mingqi Li, Chengdu, CN;

Han Wang, Chengdu, CN;

Qimin Deng, Chengdu, CN;

Zuoyong Cheng, Chengdu, CN;

Maoliang Li, Chengdu, CN;

Yonglong Zeng, Chengdu, CN;

Xue Jiang, Chengdu, CN;

Yuchun Duan, Chengdu, CN;

Sanping Zhu, Chengdu, CN;

Dezhong Wen, Chengdu, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6541 (2006.01); C07F 9/547 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07F 9/6541 (2013.01); C07F 9/4031 (2013.01); C07F 9/5475 (2013.01);
Abstract

The present disclosure relates to a new diphosphonate compound, and the method to prepare the above new diphosphonate compound. The new diphosphonate compound exhibits an activity in inhibiting osteoclast equivalent to alendronate sodium, and a higher activity in affecting the proliferation of osteoplast than the positive control compounds, but the positive control exhibits a weaker effect on osteoblast proliferation. In experimental examples, an administration schedule for the diphosphonate compound is provided.


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