The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Oct. 23, 2012
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Cisen Pharmaceutical Co., Ltd., Jining, CN;
Hong Liu, Shanghai, CN;
Jia Li, Shanghai, CN;
Jian Li, Shanghai, CN;
Jingya Li, Shanghai, CN;
Jiang Wang, Shanghai, CN;
Mingbo Su, Shanghai, CN;
Jie Lian, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Kaixian Chen, Shanghai, CN;
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Cisen Pharmaceutical Co., Ltd., Jining, CN;
Abstract
Disclosed are new thienyl [3,2-d] pyrimidin-4-one compounds shown as the general formula (I), preparation method, pharmaceutical compositions and pharmacological use thereof. The compounds are strong DPPIV (dipeptide peptidase IV) inhibitors and can treat type II diabetes through well inhibiting DPPIV indirectly increasing the content of GLP-1 in vivo and inducing a series of physiological actions in vivo. Therefore, the compounds could be developed as new promising drugs for treating diabetes.