The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Jul. 08, 2013
Applicant:
Bcworld Pharm. Co., Ltd., Yeoju-Gun, Kyunggi-Do, KR;
Inventors:
Hearan Suh, Seoul, KR;
Sang Kyu Nam, Seoul, KR;
Jong Sun Lee, Gyeonddi-Do, KR;
Seung Ki Kim, Gyeonggi-Do, KR;
Assignee:
BCWORLD PHARM. CO., LTD., Yeoju-Gun, KR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 401/06 (2006.01); C07D 241/04 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); C07D 241/04 (2013.01); C07D 401/04 (2013.01);
Abstract
A method for preparing an imatinib base includes reacting 4-(4-methyl-piperazinomethyl)-benzoic acid with a 2,2'-dibenzothiazolyl disulfide derivative in the presence of a phosphine derivative to prepare a novel thioester compound and preparing an imatinib base using the thioester compound as a reaction intermediate. With the method, imatinib base in higher yield and/or purity can be prepared cost-effectively.