The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
May. 04, 2011
Applicant:
James Malecha, San Diego, CA (US);
Inventor:
James Malecha, San Diego, CA (US);
Assignee:
FerroKin Biosciences, Inc., Wayne, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07D 233/28 (2006.01); C07D 263/16 (2006.01); C07D 277/12 (2006.01); C07D 277/56 (2006.01); A61K 31/5377 (2006.01); A61K 31/421 (2006.01); A61K 31/4172 (2006.01); A61K 31/426 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
C07D 263/16 (2013.01); C07D 231/14 (2013.01); C07D 233/28 (2013.01); C07D 277/12 (2013.01); C07D 277/56 (2013.01);
Abstract
Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogs, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.