The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Apr. 13, 2012
Applicants:
Takanobu Kuroita, Osaka, JP;
Yasuhiro Imaeda, Ann Arbor, MI (US);
Kouichi Iwanaga, Osaka, JP;
Naohiro Taya, Osaka, JP;
Hidekazu Tokuhara, Osaka, JP;
Inventors:
Takanobu Kuroita, Osaka, JP;
Yasuhiro Imaeda, Ann Arbor, MI (US);
Kouichi Iwanaga, Osaka, JP;
Naohiro Taya, Osaka, JP;
Hidekazu Tokuhara, Osaka, JP;
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/14 (2006.01); C07D 233/90 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 407/12 (2006.01); C07D 409/06 (2006.01); C07D 409/14 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/08 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 233/90 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 407/12 (2013.01); C07D 409/06 (2013.01); C07D 409/14 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 495/04 (2013.01);
Abstract
Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.