The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Apr. 01, 2011
Michael H. Gelb, Seattle, WA (US);
Frantisek Turecek, Seattle, WA (US);
James Bollinger, Seattle, WA (US);
Michael H. Gelb, Seattle, WA (US);
Frantisek Turecek, Seattle, WA (US);
James Bollinger, Seattle, WA (US);
University of Washington, Seattle, WA (US);
Abstract
Method and reagent for converting a carboxylic acid to a positively charge amide are described. The method and reagent facilitate positive ion mass spectral analysis of carboxylic acids. The method includes reacting a carboxylic acid with a compound having formula I: wherein A and B are aromatic rings, ring A includes a quaternized nitrogen and has n additional ring atoms, each additional ring atom optionally substituted with an Rgroup, and n is an integer from 4 to 10, and ring B includes a carbon atom and has m additional ring atoms, each additional ring atom optionally substituted with an Rgroup, and m is an integer from 4 to 10. The compound includes at least one Ror Rgroup, and the at least one Rand Rgroup is -L-N(Z)H; and Xis a counterion.