The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 2015
Filed:
Mar. 09, 2010
Applicants:
Jeffrey A. Toretsky, Silver Spring, MD (US);
Aykut Üren, Rockville, MD (US);
Milton Lang Brown, Brookville, MD (US);
Yali Kong, Centreville, VA (US);
Inventors:
Jeffrey A. Toretsky, Silver Spring, MD (US);
Aykut Üren, Rockville, MD (US);
Milton Lang Brown, Brookville, MD (US);
Yali Kong, Centreville, VA (US);
Assignee:
Georgetown University, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); C07D 209/38 (2006.01); A61K 38/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
C07D 209/38 (2013.01); A61K 38/00 (2013.01); C07D 401/06 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01);
Abstract
Peptides and compounds are provided that function as EWS-FLI1 protein inhibitors. The peptides and compounds have utility in the treatment of Ewing's sarcoma family of tumors. Also provided are methods of preparing the compounds and assays for identifying inhibitors of EWS-FLI1 protein.