The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Mar. 14, 2013
Applicant:

Los Alamos National Security, Llc, Los Alamos, NM (US);

Inventors:

Pat J. Unkefer, Los Alamos, NM (US);

Rodolfo A. Martinez, Santa Fe, NM (US);

David R. Glass, Las Vegas, NM (US);

Assignees:

Los Alamos National Security, LLC, Los Alamos, NM (US);

New Mexico Highlands University, Las Vegas, NM (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 229/00 (2006.01); C07C 253/30 (2006.01); C07C 231/06 (2006.01);
U.S. Cl.
CPC ...
C07C 253/30 (2013.01); C07C 231/06 (2013.01);
Abstract

A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with sodium ethoxide in ethanol to form a reaction mixture, and afterward adding ethyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl-2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl-2-cyano-3-hydroxybutenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with aqueous sodium hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid.


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