The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Sep. 11, 2012
Applicants:

Ting Xu, Berkeley, CA (US);

He Dong, Albany, CA (US);

Jessica Shu, San Francisco, CA (US);

Inventors:

Ting Xu, Berkeley, CA (US);

He Dong, Albany, CA (US);

Jessica Shu, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 47/48038 (2013.01); A61K 47/48215 (2013.01); A61K 47/488 (2013.01); B82Y 5/00 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01);
Abstract

The present invention provides a conjugate having a peptide with from about 10 to about 100 amino acids, wherein the peptide adopts a helical structure. The conjugate also includes a first polymer covalently linked to the peptide, and a hydrophobic moiety covalently linked to the N-terminus of the peptide, wherein the hydrophobic moiety comprises a second polymer or a lipid moiety. The present invention also provides helix bundles form by self-assembling the conjugates, and particles formed by self-assembling the helix bundles. Methods of preparing the helix bundles and particles are also provided.


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