The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Mar. 15, 2013
Applicant:

Insite Vision Corporation, Alameda, CA (US);

Inventors:

Lyle M. Bowman, Pleasanton, CA (US);

Sui Yen Eddie Hou, Foster City, CA (US);

Tang Nguyen, Alameda, CA (US);

Assignee:

INSITE VISION CORPORATION, Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A61K 47/02 (2006.01); A61K 31/573 (2006.01); A61K 31/7052 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2006.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 47/02 (2013.01); A61K 31/573 (2013.01); A61K 31/7052 (2013.01); A61K 9/0048 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01);
Abstract

Provided is concentrated aqueous azithromycin formulation from about from about 2%-20%, and a method of making a concentrated aqueous azithromycin formulation which includes preparing and sterilizing a first solution comprising a strong base to form a sterilized solution, dissolving the azithromycin in an aqueous solution comprising an acid consisting essentially of a strong acid, and adding the aqueous solution comprising the strong acid to the sterilized solution comprising the strong base. The strong acid has a pKa less than about −1.74 and the method is carried out without addition or use of a weak acid.


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