The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

Oct. 22, 2013
Applicants:

Karen Guillemin, Eugene, OR (US);

Allison Banse, Eugene, OR (US);

Inventors:

Karen Guillemin, Eugene, OR (US);

Allison Banse, Eugene, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/106 (2006.01); A61K 38/16 (2006.01); G01N 33/68 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 38/164 (2013.01); G01N 33/6893 (2013.01); G01N 33/57419 (2013.01); G01N 2333/195 (2013.01); G01N 2800/065 (2013.01);
Abstract

Disclosed herein are methods of increasing epithelial cell proliferation (such as intestinal epithelial cell proliferation) by contacting epithelial cells with one or more CBPs. In some examples, the methods include administering the CBP to a subject, such as a subject in need of increased epithelial cell proliferation. Also disclosed herein are methods of identifying a subject having or at risk of developing hyperproliferation of epithelial cells (such as intestinal epithelial cells). Further disclosed are methods of decreasing epithelial cell proliferation by decreasing expression and/or activity of a CBP and methods of identifying inhibitors of epithelial cell proliferation and/or CBP activity.


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