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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9044421 B1

PDFFull Text
Date of Patent:
Jun. 02, 2015

Filed:

Mar. 28, 2013

Treating muc1-expressing cancers with combination therapies

Applicants:

Genus Oncology, Llc., Vernon Hills, IL (US);

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Donald Kufe, Wellesley, MA (US);

Surender Kharbanda, Natick, MA (US);

Assignees:

Genus Oncology, LLC, Vernon Hills, IL (US);

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

Attorney:

Parker Highlander PLLC

Primary Examiner:

Julie Ha

Assistant Examiner:

Li Ni Komatsu

Int. Cl.
CPC ...
A61K 38/03 (2006.01); A61P 35/00 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61K 38/08 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/03 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61K 38/08 (2013.01); A61K 38/1735 (2013.01);
Abstract

The invention provides method of treating cancers that express mucin 1 (MUC1) by the administration of phosphatidylinositol 3-kinase (PI3-K) inhibitors in combination with MUC1-directed cancer therapies. The PI3-K inhibition may advantageously be combined with peptides that inhibit MUC1 oligomerization, or further with other standard anticancer therapies such as chemo-, radio- and surgical therapies.

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Kufe, Donald. (2015). Treating muc1-expressing cancers with combination therapies (U.S. Patent No. 9044421). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9044421

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