The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 2015

Filed:

May. 05, 2014
Applicants:

Universite Claude Bernard Lyon I, Villeurbanne Cedex, FR;

Centre National DE LA Recherche Scientifique, Paris Cedex, FR;

Inventors:

Alain Domard, Lyons, FR;

Laurent David, Lyons, FR;

Florence Dupasquier, Paray le Monia, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61F 13/00 (2006.01); D02G 3/00 (2006.01); D01D 5/06 (2006.01); D01F 9/00 (2006.01); D01F 11/00 (2006.01); A61K 47/36 (2006.01); A61L 27/20 (2006.01); C08J 7/04 (2006.01); C08J 7/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/70 (2013.01); Y10T 428/298 (2015.01); Y10T 428/2913 (2015.01); Y10T 428/2933 (2015.01); D01D 5/06 (2013.01); D01F 9/00 (2013.01); D01F 11/00 (2013.01); A61K 47/36 (2013.01); A61L 27/20 (2013.01); C08J 7/04 (2013.01); C08J 7/065 (2013.01); C08J 2305/08 (2013.01);
Abstract

The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.


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