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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9040725 B1

PDFFull Text
Date of Patent:
May. 26, 2015

Filed:

Mar. 10, 2014

Benzocycloheptane and benzoxepine derivatives

Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Bruno Schoentjes, Brussels, BE;

Alain Philippe Poncelet, La Manoir sur Seine, FR;

Julien Georges Pierre-Olivier Doyon, Beerse, BE;

Joannes Theodorus Maria Linders, Eindhoven, NL;

Lieven Meerpoel, Beerse, BE;

Luc August Laurentius Ver Donck, Kasterlee, BE;

Assignee:

Janssen Pharmaceutica, NV, Beerse, BE;

Attorney:

Sean C. Brock

Primary Examiner:

Nizal Chandrakumar

Int. Cl.
CPC ...
C07D 313/00 (2006.01); C07C 211/00 (2006.01); C07C 215/42 (2006.01); C07C 35/52 (2006.01); C07C 43/192 (2006.01); C07C 215/64 (2006.01); C07C 217/08 (2006.01); C07C 217/74 (2006.01); C07D 295/092 (2006.01); C07D 313/08 (2006.01); C07D 405/04 (2006.01); C07D 407/04 (2006.01); C07D 207/06 (2006.01); C07D 213/53 (2006.01); C07D 213/65 (2006.01); C07D 215/14 (2006.01); C07D 239/26 (2006.01); C07D 295/096 (2006.01); C07D 295/16 (2006.01); C07D 317/58 (2006.01);
U.S. Cl.
CPC ...
C07C 215/42 (2013.01); C07C 35/52 (2013.01); C07C 43/192 (2013.01); C07C 215/64 (2013.01); C07C 217/08 (2013.01); C07C 217/74 (2013.01); C07C 2102/12 (2013.01); C07D 295/092 (2013.01); C07D 313/08 (2013.01); C07D 405/04 (2013.01); C07D 407/04 (2013.01); C07D 207/06 (2013.01); C07D 213/53 (2013.01); C07D 213/65 (2013.01); C07D 215/14 (2013.01); C07D 239/26 (2013.01); C07D 295/096 (2013.01); C07D 295/16 (2013.01); C07D 317/58 (2013.01);
Abstract

The present invention relates to a compound of formula (I) including any stereochemically isomeric form thereof, wherein the substituents are as defined in the specification and the claims; a N-oxide thereof, a pharmaceutically acceptable salt thereof or a solvate thereof; or a pharmaceutically acceptable salt thereof. The claimed compounds are useful for the treatment of a disease, the treatment of which is affected, mediated or facilitated by activating the GHS1A-r receptor. The invention also relates to pharmaceutical compositions thereof and processes for the preparation thereof.

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