The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

May. 05, 2014
Applicant:

Nanoquantum Sciences, Inc., Bellevue, WA (US);

Inventors:

Gary W. Jones, Newcastle, WA (US);

Anatoliy L. Tatarets, Kharkov, UA;

Leonid D. Patsenker, Kharkov, UA;

Assignee:

Nanoquantum Sciences, Inc., Bellevue, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); A61K 31/404 (2006.01); A61K 31/403 (2006.01); A61N 5/10 (2006.01); C07D 401/02 (2006.01); C07D 209/58 (2006.01); C07D 209/04 (2006.01); A61K 41/00 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 417/06 (2006.01); C07D 471/10 (2006.01); C07D 487/22 (2006.01); C07D 209/08 (2006.01); C07D 209/10 (2006.01); C07D 277/62 (2006.01); C07D 293/12 (2006.01); C09B 23/08 (2006.01); C09B 62/00 (2006.01); C09B 23/10 (2006.01); C09B 47/00 (2006.01); C07D 209/18 (2006.01); C07D 209/24 (2006.01); C07D 209/60 (2006.01); C07D 277/64 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 417/06 (2013.01); C07D 471/10 (2013.01); C07D 487/22 (2013.01); C07D 209/08 (2013.01); C07D 209/10 (2013.01); C07D 277/62 (2013.01); C07D 293/12 (2013.01); A61K 31/403 (2013.01); A61K 31/404 (2013.01); A61K 31/438 (2013.01); A61N 5/10 (2013.01); C07D 209/04 (2013.01); C07D 209/58 (2013.01); C07D 401/02 (2013.01); C09B 23/086 (2013.01); C09B 62/00 (2013.01); A61K 41/0071 (2013.01); C09B 23/105 (2013.01); C09B 47/00 (2013.01); C07D 209/18 (2013.01); C07D 209/24 (2013.01); C07D 209/60 (2013.01); C07D 277/64 (2013.01);
Abstract

Halo-organic heterocyclic compounds are described, in which at least two halogen atoms are bound to a nitrogen-containing heterocyclic terminal moiety of the compound, with at least one of such halogen atoms being iodine or bromine. Also described are polymethine dyes based on these heterocyclic compounds, and dendrimeric compounds and conjugates of such polymethine dyes. The polymethine dyes are characterized by enhanced properties, e.g., brightness, photostability, sensitivity and/or selective affinity that make them useful to target cancer cells, pathogenic microorganisms, and/or other biological materials, in applications such as photodynamic therapy, photodynamic antimicrobial chemotherapy (PACT), cancer treatment, selective removal or attachment of biological materials, antimicrobial coating materials, and other diagnostic, theranostic, spectrum shifting, deposition/growth, and analytic applications.


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