The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Dec. 16, 2010
Gregor James Macdonald, Zoersel, BE;
Andrés Avelino Trabanco-suárez, Olias del Rey (Toledo), ES;
Susana Conde-ceide, Toledo, ES;
Gary John Tresadern, Toledo, ES;
José Manuel Bartolomé-nebreda, Toledo, ES;
Joaquin Pastor-fernández, Toledo, ES;
Gregor James MacDonald, Zoersel, BE;
Andrés Avelino Trabanco-Suárez, Olias del Rey (Toledo), ES;
Susana Conde-Ceide, Toledo, ES;
Gary John Tresadern, Toledo, ES;
José Manuel Bartolomé-Nebreda, Toledo, ES;
Joaquin Pastor-Fernández, Toledo, ES;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to novel bicyclic thiazoles which are positive allosteric modulators of the metabotropic glutamate receptor subtype 5 ('mGluR5') and which are useful for the treatment or prevention of disorders associated with glutamate dysfunction and diseases in which the mGluR5 subtype of receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which mGluR5 is involved.