The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Apr. 09, 2010
Applicants:
Peter X. Wang, Creve Coeur, MO (US);
Tao Jiang, Chesterfield, MO (US);
Narayanasamy Gurusamy, Ballwin, MO (US);
Catherine K. Jung, Skokie, IL (US);
Inventors:
Peter X. Wang, Creve Coeur, MO (US);
Tao Jiang, Chesterfield, MO (US);
Narayanasamy Gurusamy, Ballwin, MO (US);
Catherine K. Jung, Skokie, IL (US);
Assignee:
Mallinckrodt LLC, Hazelwood, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 489/02 (2006.01); C07D 489/04 (2006.01);
U.S. Cl.
CPC ...
C07D 489/04 (2013.01); C07D 489/02 (2013.01);
Abstract
The present invention provides processes for the preparation of saturated ketone morphinan compounds. In particular, the invention provides processes for the conversion of a morphinan comprising an allyl alcohol ring moiety into a morphinan comprising a saturated ketone ring moiety by an isomerization reaction catalyzed by an inorganic salt of a late transition metal.