The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Jul. 01, 2011
Applicants:
Yian Shi, Beijing, CN;
Xianyou Peng, Beijing, CN;
Peijun LI, Beijing, CN;
Inventors:
Assignee:
Institute of Chemistry Chinese Academy of Sciences, Beijing, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/24 (2006.01); C07D 239/34 (2006.01); C07D 239/60 (2006.01);
U.S. Cl.
CPC ...
C07D 239/34 (2013.01); C07D 239/60 (2013.01);
Abstract
Disclosed is a method for preparing optically pure (+)-ambrisentan and (+)-darusentan, comprising: firstly catalyzing the asymmetric epoxidation of a β-unsaturated alkene using a chiral ketone derived from fructose or a hydrate thereof as a catalyst, and then subjecting the product to an epoxy compound ring-opening reaction and substitution reaction successively to obtain optically pure (+)-ambrisentan and (+)-darusentan.
Shi, Yian. (2015). Method for preparing optically pure (+)-ambrisentan and (+)-darusentan (U.S. Patent No. 9040698). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9040698
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile